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• Rest easy: MIT study confirms melatonin's value as sleep aid - MIT News Office: The researchers also found, however, that commercially available melatonin pills contain 10 times the effective amount. And at that dose, "after a few days it stops working," said Wurtman, director of MIT's Clinical Research Center and the Cecil H. Green Distinguished Professor. When the melatonin receptors in the brain are exposed to too much of the hormone, they become unresponsive. When Wurtman first discovered the efficacy of small doses of melatonin, he and MIT patented its use for dosages up to one milligram. Because the FDA defined the hormone as a dietary supplement, however, manufacturers were free to sell it in much higher dosages, "even though we knew they wouldn't work," Wurtman said. As a result, until recently the hormone was commercially unavailable to the public in small doses. "People who knew that small doses were best often bought the high-dose pills, then divided them with a knife," Wurtman said. "But that's not very accurate." ;
• Media in Transition 6
• MIT's Introduction to Algorithms, Lecture 16: Greedy Algorithms - good coders code, great reuse
• Center for Coordination Science @ MIT Sloan
• Terrafugia's car of the future: It flies - Dec. 4, 2008
• Free Online Course Materials from MIT OpenCourseWare
• MIT's Introduction to Algorithms, Lectures 1 and 2: Analysis of Algorithms - good coders code, great reuse

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